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Cardiology Clinical Guidelines
Heart Failure Clinical Guidelines and Resources
The American College of Cardiology (ACC) and the American Heart Association (AHA) released the updated clinical guidelines in 2022 on the management of heart failure, replacing the 2017 update. The following is a brief… Read the clinical guidelines summary >
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Listen and Learn: DDx Podcast
Listen to episode 2, Code Blue, of our third season of the DDx podcast to discover how one rare disease almost had a fatal impact on the heart.
Understand risk factors beyond tobacco use for COPD in patients immigrating from low-resource countries. Start activity >
Recognize how symptoms of pertussis can manifest and how to formulate a treatment plan. Start activity >
Learn how this specific type of tachycardia manifests on an electrocardiogram. Start activity >
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Rice-Based Diet and Cardiovascular Disease Mortality in Japan: From the Takayama Study | PubMed
“We aimed to evaluate the association between rice consumption as grain dishes and cardiovascular disease mortality in comparison with bread and noodle consumption … In Japan, choosing rice as a grain dish is likely to be accompanied by healthier foods as side dishes, which may have a potential role in the prevention of cardiovascular disease.”
ALOX15-launched PUFA-phospholipids Peroxidation Increases the Susceptibility of Ferroptosis in Ischemia-induced Myocardial Damage | PubMed
“Myocardial ischemia/reperfusion (I/R) injury is a classic type of cardiovascular disease characterized by injury to cardiomyocytes leading to various forms of cell death. It is believed that irreversible myocardial damage resulted from I/R occurs due to oxidative stress evoked during the reperfusion phase … Collectively, our results reveal that ALOX15 induction in the ischemia phase acts as a “burning point” to ignite phospholipid oxidization into ferroptotic signals.”
Spatial Multi-omic Map of Human Myocardial Infarction | PubMed
“Here we generate an integrative high-resolution map of human cardiac remodelling after myocardial infarction using single-cell gene expression, chromatin accessibility and spatial transcriptomic profiling of multiple physiological zones at distinct time points in myocardium from patients with myocardial infarction and controls … Our data elucidate the molecular principles of human myocardial tissue organization, recapitulating a gradual cardiomyocyte and myeloid continuum following ischaemic injury.”