A Figure 1 podcast
A Figure 1 podcast

DDx: A Podcast About How Doctors Think

DDx is medical shorthand for differential diagnosis, and this is a podcast about how doctors think and learn on the job. It’s hosted by Dr. Raj Bhardwaj and is produced by Figure 1, the global knowledge-sharing platform for medicine.

Latest Episodes


Diagnosing a Complex and Mysterious Form of Paediatric Epilepsy

A toddler’s parents noticed him having muscle twitches before falling asleep and when waking up. They’re told nothing is wrong. This episode of DDx reminds us that sometimes when you hear hoofbeats, it really is a zebra.


Diagnosing a Complex and Mysterious Form of Paediatric Epilepsy

A child was referred to a specialist on the suspicion he has pediatric epilepsy, a complicated and fickle condition. In this episode of DDx, we explore a case with several peculiar symptoms and diagnostic test results that baffled doctors. The answer may lie in genetic testing.


Mapping a Complicated Genetic History of Epilepsy

A 5-month-old was brought to the emergency department with staring episodes. In this episode of DDx, we’re reminded that even when initial tests come back normal, keep thinking about the patient in front of you and probe parents for any new signs.


The Many Questions and Few Answers of a Rare Disease Diagnosis

A toddler has episodes where his face changes, his arms shoot up, and he collapses. On this episode of the podcast, we address when rare disease diagnoses offer more questions than answers, and treatment options don’t lead to a cure.


Classic Symptoms of Rare Diseases and Avoiding Diagnostic Odysseys

Rare diseases are … rare … which makes even textbook cases difficult to diagnose. In this episode, we’ll talk about the patterns and characterizations of a rare disease and how we can avoid diagnostic odysseys.


Rare Pediatric Epilepsies and the Answers You Least Expect

Even when you’ve studied a disease for most of your career, a patient can still surprise you and deliver an answer you didn’t expect, especially in the world of rare diseases. Follow six neurologists who specialize in pediatric epilepsies on their journeys to spot the zebra in the herd of horses. 

New episodes are released weekly!

Subscribe for exclusive updates about season 5.

The information shared in DDx is not intended nor implied to be a substitute for professional medical advice. It is provided for educational purposes only.

Catch up on season 3

Meet the doctors searching for the zebra among a herd of horses. Explore the challenges in distinguishing rare diseases from common ones, and how to recognize them when the stakes are life and death.

Catch up on season 4

In this season, we explore the infinite universe inside the tiny molecules of our DNA, and look at the technology with the potential to reshape our approach to treating many genetic diseases.

About DDx

DDx is medical shorthand for differential diagnosis, a system of analysis designed to identify the root cause of complex patient symptoms. This is a medical podcast about how doctors think and learn on the job — exploring complex areas of medicine and difficult medical cases. The show is hosted by Dr. Raj Bhardwaj and produced by Figure 1.